{"id":446,"date":"2024-02-24T08:43:34","date_gmt":"2024-02-24T08:43:34","guid":{"rendered":"https:\/\/rhirota.hiroshima-u.ac.jp\/?page_id=446"},"modified":"2025-02-26T13:08:08","modified_gmt":"2025-02-26T13:08:08","slug":"research-2","status":"publish","type":"page","link":"https:\/\/rhirota.hiroshima-u.ac.jp\/?page_id=446","title":{"rendered":"Research-2"},"content":{"rendered":"\t\t<div data-elementor-type=\"wp-page\" data-elementor-id=\"446\" class=\"elementor elementor-446\" data-elementor-post-type=\"page\">\n\t\t\t\t<div class=\"elementor-element elementor-element-07fd45d e-flex e-con-boxed e-con e-parent\" data-id=\"07fd45d\" data-element_type=\"container\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-36ea05b elementor-widget elementor-widget-heading\" data-id=\"36ea05b\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">Research<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-b2b9c10 elementor-widget elementor-widget-heading\" data-id=\"b2b9c10\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">\u7814\u7a76\u5185\u5bb9<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-ce18319 e-flex e-con-boxed e-con e-parent\" data-id=\"ce18319\" data-element_type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-7c27ce0 elementor-widget elementor-widget-heading\" data-id=\"7c27ce0\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">2\uff0e\u30d0\u30af\u30c6\u30ea\u30a2\u306e\u30ea\u30f3\u9178\u4ee3\u8b1d\u7d4c\u8def\u306e\u89e3\u660e\u3068\u5fdc\u7528\n<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-02a0896 elementor-widget-divider--view-line elementor-widget elementor-widget-divider\" data-id=\"02a0896\" data-element_type=\"widget\" data-widget_type=\"divider.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<div class=\"elementor-divider\">\n\t\t\t<span class=\"elementor-divider-separator\">\n\t\t\t\t\t\t<\/span>\n\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-b011527 e-flex e-con-boxed e-con e-parent\" data-id=\"b011527\" data-element_type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-5d777f0 elementor-widget elementor-widget-heading\" data-id=\"5d777f0\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h3 class=\"elementor-heading-title elementor-size-default\">\u30ea\u30f3\u306e\u6027\u8cea<\/h3>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-68c6230 elementor-widget elementor-widget-text-editor\" data-id=\"68c6230\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p><span style=\"font-weight: 400;\">\u30ea\u30f3\u9178\uff08HPO<\/span><span style=\"font-weight: 400;\">4<\/span><span style=\"font-weight: 400;\">2-<\/span><span style=\"font-weight: 400;\">)\u306f\u751f\u7269\u306e\u5fc5\u9808\u5143\u7d20\u3067\u3042\u308a\u3001\u5168\u3066\u306e\u751f\u7269\u304c\u5fc5\u8981\u3068\u3059\u308b\u6804\u990a\u5869\u3067\u3042\u308b\u305f\u3081\u3001\u74b0\u5883\u4e2d\u3067\u306f\u6b20\u4e4f\u3057\u304c\u3061\u306b\u306a\u308a\u307e\u3059\u3002\u3055\u3089\u306b\u3001\u9244\u3084\u30ab\u30eb\u30b7\u30a6\u30e0\u306a\u3069\u3068\u5bb9\u6613\u306b\u7d50\u5408\u3057\u3001\u4e0d\u6eb6\u6027\u306e\u5869\u3092\u5f62\u6210\u3059\u308b\u3068\u3044\u3046\u7269\u7406\u5316\u5b66\u7684\u6027\u8cea\u3082\u3001\u30ea\u30f3\u306e\u7372\u5f97\u304c\u56f0\u96e3\u306b\u306a\u308b\u8981\u56e0\u3068\u306a\u3063\u3066\u3044\u307e\u3059\u3002<\/span><\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-ed5dcde e-flex e-con-boxed e-con e-parent\" data-id=\"ed5dcde\" data-element_type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-8f15ca4 elementor-widget elementor-widget-heading\" data-id=\"8f15ca4\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h3 class=\"elementor-heading-title elementor-size-default\">\u30d0\u30af\u30c6\u30ea\u30a2\u306e\u30ea\u30f3\u5229\u7528\u80fd\u529b<\/h3>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-a636558 elementor-widget elementor-widget-text-editor\" data-id=\"a636558\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p><span style=\"font-weight: 400;\">\u30d0\u30af\u30c6\u30ea\u30a2\u306f\u512a\u308c\u305f\u30ea\u30f3\u306e\u53d6\u308a\u8fbc\u307f\u3068\u84c4\u7a4d\u80fd\u529b\u3092\u6301\u3061\u3001\u4f4e\u6fc3\u5ea6\u306e\u30ea\u30f3\u3067\u3082\u52b9\u7387\u7684\u306b\u53d6\u308a\u8fbc\u3080\u3053\u3068\u304c\u3067\u304d\u3001\u84c4\u7a4d\u3057\u3066\u98e2\u9913\u72b6\u614b\u306b\u5099\u3048\u308b\u30b7\u30b9\u30c6\u30e0\u3092\u6709\u3057\u3066\u3044\u307e\u3059\u3002\u307e\u305f\u3001\u9ad8\u7b49\u751f\u7269\u3084\u690d\u7269\u306a\u3069\u306e\u751f\u7269\u304c\u30ea\u30f3\u9178\uff08HPO<\/span><span style=\"font-weight: 400;\">4<\/span><span style=\"font-weight: 400;\">2-<\/span><span style=\"font-weight: 400;\">)\u3057\u304b\u5229\u7528\u3067\u304d\u306a\u3044\u306e\u306b\u5bfe\u3057\u3001\u30d0\u30af\u30c6\u30ea\u30a2\u306f\u3055\u307e\u3056\u307e\u306a\u5f62\u614b\u306e\u30ea\u30f3\u5316\u5408\u7269\u3092\u5229\u7528\u3067\u304d\u308b\u80fd\u529b\u3092\u5099\u3048\u3066\u3044\u307e\u3059\u3002<\/span><\/p><p><span style=\"font-weight: 400;\">\u305f\u3068\u3048\u3070\u3001\u30ea\u30f3\u306f\u5316\u5b66\u7684\u306b\u591a\u304f\u306e\u751f\u7269\u304c\u5229\u7528\u3067\u304d\u306a\u3044\u9084\u5143\u72b6\u614b\uff08\u9178\u7d20\u539f\u5b50\u6570\u304c4\u3064\u4ee5\u4e0b\uff09\u3092\u53d6\u308b\u3053\u3068\u304c\u3067\u304d\u307e\u3059\u304c\u3001\u4e00\u90e8\u306e\u30d0\u30af\u30c6\u30ea\u30a2\u306f\u3053\u306e\u3088\u3046\u306a\u5f62\u614b\u306e\u30ea\u30f3\u3092\u4ee3\u8b1d\u3059\u308b\u80fd\u529b\u3092\u3082\u3064\u3053\u3068\u304c\u660e\u3089\u304b\u306b\u306a\u3063\u3066\u3044\u307e\u3059\u3002\u30d0\u30af\u30c6\u30ea\u30a2\u306b\u591a\u69d8\u306a\u30ea\u30f3\u7372\u5f97\u80fd\u529b\u304c\u5099\u308f\u3063\u3066\u3044\u308b\u3053\u3068\u306f\u3001\u30ea\u30f3\u304c\u751f\u7269\u306b\u3068\u3063\u3066\u3044\u304b\u306b\u91cd\u8981\u3067\u3042\u308b\u304b\u3092\u7269\u8a9e\u308b\u3082\u306e\u3067\u3059\u3002\u307e\u305f\u3001\u3053\u3046\u3057\u305f\u9ad8\u5ea6\u306a\u30b7\u30b9\u30c6\u30e0\u3092\u767a\u9054\u3055\u305b\u3066\u304d\u305f\u30d0\u30af\u30c6\u30ea\u30a2\u306e\u5b58\u5728\u306b\u306f\u3001\u751f\u7269\u306e\u67d4\u8edf\u6027\u3084\u9811\u5f37\u6027\u3092\u3042\u3089\u305f\u3081\u3066\u5b9f\u611f\u3055\u305b\u3089\u308c\u307e\u3059\u3002<\/span><\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-e4dd40e elementor-widget elementor-widget-image\" data-id=\"e4dd40e\" data-element_type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t<figure class=\"wp-caption\">\n\t\t\t\t\t\t\t\t\t\t<img fetchpriority=\"high\" decoding=\"async\" width=\"981\" height=\"569\" src=\"https:\/\/rhirota.hiroshima-u.ac.jp\/wp-content\/uploads\/2025\/02\/unnamed-2.png\" class=\"attachment-full size-full wp-image-579\" alt=\"\" srcset=\"https:\/\/rhirota.hiroshima-u.ac.jp\/wp-content\/uploads\/2025\/02\/unnamed-2.png 981w, https:\/\/rhirota.hiroshima-u.ac.jp\/wp-content\/uploads\/2025\/02\/unnamed-2-300x174.png 300w, https:\/\/rhirota.hiroshima-u.ac.jp\/wp-content\/uploads\/2025\/02\/unnamed-2-768x445.png 768w\" sizes=\"(max-width: 981px) 100vw, 981px\" \/>\t\t\t\t\t\t\t\t\t\t\t<figcaption class=\"widget-image-caption wp-caption-text\">\u30d0\u30af\u30c6\u30ea\u30a2\u306e\u30ea\u30f3\u4ee3\u8b1d\u306e\u5168\u4f53\u50cf<br>\u5927\u8178\u83cc\u3092\u542b\u3080\u8907\u6570\u7a2e\u985e\u306e\u30d0\u30af\u30c6\u30ea\u30a2\u306b\u3088\u3063\u3066\u660e\u3089\u304b\u306b\u3055\u308c\u3066\u3044\u308b\u30ea\u30f3\u4ee3\u8b1d\u7d4c\u8def\u3002 <br>\u30ea\u30f3\u306e\u7d30\u80de\u8cea\u5185\u6fc3\u5ea6\u306fmM\uff08\u30df\u30ea\u30e2\u30eb\/L\uff09\u3067\u3042\u308a\u3001\u5916\u90e8\u74b0\u5883(nM\u301cmM\u30ec\u30d9\u30eb\uff09\u306e\u6570\u5341\u4e07\u301c\u767e\u4e07\u500d\u4ee5\u4e0a\u306b\u6fc3\u7e2e\u3055\u308c\u3066\u3044\u307e\u3059\u3002 <br>\u30d0\u30af\u30c6\u30ea\u30a2\u306f\u3001\u4f4e\u6fc3\u5ea6\u306e\u30ea\u30f3\u3067\u3082\u53d6\u308a\u8fbc\u3080\u3053\u3068\u304c\u3067\u304d\u308b\u8f38\u9001\u4f53\u3084\u3001\u5f62\u614b\u306e\u7570\u306a\u308b\u30ea\u30f3\u3092\u30ea\u30f3\u9178\u306b\u5909\u63db\u3059\u308b\u591a\u69d8\u306a\u9175\u7d20\u3092\u6301\u3063\u3066\u3044\u307e\u3059\u3002<\/figcaption>\n\t\t\t\t\t\t\t\t\t\t<\/figure>\n\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-7395505 e-flex e-con-boxed e-con e-parent\" data-id=\"7395505\" data-element_type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-e11b427 elementor-widget elementor-widget-heading\" data-id=\"e11b427\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h3 class=\"elementor-heading-title elementor-size-default\">\u7814\u7a76\u3078\u306e\u5c55\u958b<\/h3>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-41421ba elementor-widget elementor-widget-text-editor\" data-id=\"41421ba\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p><span style=\"font-weight: 400;\">\u30d0\u30af\u30c6\u30ea\u30a2\u304c\u6301\u3064\u30ea\u30f3\u4ee3\u8b1d\u306b\u95a2\u308f\u308b\u7279\u6b8a\u306a\u30bf\u30f3\u30d1\u30af\u8cea\u306f\u3001\u305d\u308c\u81ea\u8eab\u304c\u975e\u5e38\u306b\u8208\u5473\u6df1\u3044\u7814\u7a76\u5bfe\u8c61\u3067\u3042\u308b\u3068\u540c\u6642\u306b\u3001\u3053\u306e\u80fd\u529b\u3092\u6d3b\u7528\u3059\u308b\u3053\u3068\u3067\u3001\u5f93\u6765\u306e\u30d0\u30a4\u30aa\u30c6\u30af\u30ce\u30ed\u30b8\u30fc\u3067\u306f\u70ba\u3057\u5f97\u306a\u3044\u65b0\u3057\u3044\u6280\u8853\u958b\u767a\u306e\u53ef\u80fd\u6027\u3092\u3082\u305f\u3089\u3057\u307e\u3059\u3002\u79c1\u305f\u3061\u306f\u30d0\u30af\u30c6\u30ea\u30a2\u306e\u30ea\u30f3\u306e\u5229\u7528\u80fd\u529b\u3092\u7406\u89e3\u3057\u3001\u305d\u306e\u6a5f\u80fd\u3092\u30ea\u30f3\u306e\u8cc7\u6e90\u554f\u984c\u3084\u3001\u5fae\u751f\u7269\u3092\u5229\u7528\u3057\u305f\u7269\u8cea\u751f\u7523\u306b\u304a\u3051\u308b\u4ee3\u8b1d\u30fb\u5897\u6b96\u306e\u30b3\u30f3\u30c8\u30ed\u30fc\u30eb\u306a\u3069\u3001\u69d8\u3005\u306a\u5206\u91ce\u306b\u8ca2\u732e\u3059\u308b\u30d7\u30e9\u30c3\u30c8\u30d5\u30a9\u30fc\u30e0\u6280\u8853\u3068\u3057\u3066\u958b\u767a\u3059\u308b\u3053\u3068\u3092\u884c\u3063\u3066\u3044\u307e\u3059\u3002<\/span><\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-af59cc1 elementor-widget elementor-widget-image\" data-id=\"af59cc1\" data-element_type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t<figure class=\"wp-caption\">\n\t\t\t\t\t\t\t\t\t\t<img decoding=\"async\" width=\"294\" height=\"199\" src=\"https:\/\/rhirota.hiroshima-u.ac.jp\/wp-content\/uploads\/2025\/02\/unnamed-1.jpg\" class=\"attachment-large size-large wp-image-583\" alt=\"\" \/>\t\t\t\t\t\t\t\t\t\t\t<figcaption class=\"widget-image-caption wp-caption-text\">\u907a\u4f1d\u5b50\u5909\u7570\u306b\u3088\u3063\u3066\u30ea\u30f3\u9178\u306e\u5438\u53ce\u3068\u84c4\u7a4d\u80fd\u529b\u3092\u9ad8\u3081\u305f\u30d0\u30af\u30c6\u30ea\u30a2 <br>\u7121\u6a5f\u30ea\u30f3\u9178\u306e\u30dd\u30ea\u30de\u30fc\u3067\u3042\u308b\u30dd\u30ea\u30ea\u30f3\u9178\uff08\u9ec4\u8272\u3044\u9846\u7c92\uff09\u3068\u3057\u3066\u30ea\u30f3\u304c\u84c4\u7a4d\u3055\u308c\u3066\u3044\u308b\u3002<br> \u30ea\u30f3\u542b\u91cf\u306f\u5929\u7136\u306e\u30ea\u30f3\u9271\u77f3\u306b\u5339\u6575\u3059\u308b\u3002<\/figcaption>\n\t\t\t\t\t\t\t\t\t\t<\/figure>\n\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-bf565ae e-flex e-con-boxed e-con e-parent\" data-id=\"bf565ae\" data-element_type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-c232635 elementor-widget elementor-widget-spacer\" data-id=\"c232635\" data-element_type=\"widget\" data-widget_type=\"spacer.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<div class=\"elementor-spacer\">\n\t\t\t<div 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